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. 2020 Apr 3;11:1654. doi: 10.1038/s41467-020-15487-3

Table 2.

Sensitivity and specificity with AUCs and CI using pGold chip and CIA.

CIAa pGoldb
Sensitivity-cTnI 59.82% 100%
Specificity-cTnI 70.54% 95.54%
AUC-cTnIc 0.662 0.976
95% CId 0.590–0.734 0.950–1.000
p value-cTnIe 0.000023 2.85 × E−11
Sensitivity-CK-MB 24.11% 86.61%
Specificity-CK-MB 98.21% 66.07%
AUC-CK-MBc 0.614 0.821
95% CId 0.537–0.692 0.786–0.886
p value-CK-MBe 0.000493 0.000338

aSensitivity and specificity by CIA were obtained at the cutoffs of 0.04 ng mL−1 for cTnI and 4 ng mL−1 for CK-MB.

bSensitivity and specificity by pGold chip were obtained at the lowered cutoffs of 0.03 ng mL−1 for cTnI and 3.13 ng mL−1 for CK-MB.

cAUCs were obtained using the SPSS software (version 19.0, SPSS Inc., Chicago).

dCI was calculated based on the Clopper–Pearson method.

ep-Value was calculated based on the two-sided Student’s t-test.