Table 2.
CIAa | pGoldb | |
---|---|---|
Sensitivity-cTnI | 59.82% | 100% |
Specificity-cTnI | 70.54% | 95.54% |
AUC-cTnIc | 0.662 | 0.976 |
95% CId | 0.590–0.734 | 0.950–1.000 |
p value-cTnIe | 0.000023 | 2.85 × E−11 |
Sensitivity-CK-MB | 24.11% | 86.61% |
Specificity-CK-MB | 98.21% | 66.07% |
AUC-CK-MBc | 0.614 | 0.821 |
95% CId | 0.537–0.692 | 0.786–0.886 |
p value-CK-MBe | 0.000493 | 0.000338 |
aSensitivity and specificity by CIA were obtained at the cutoffs of 0.04 ng mL−1 for cTnI and 4 ng mL−1 for CK-MB.
bSensitivity and specificity by pGold chip were obtained at the lowered cutoffs of 0.03 ng mL−1 for cTnI and 3.13 ng mL−1 for CK-MB.
cAUCs were obtained using the SPSS software (version 19.0, SPSS Inc., Chicago).
dCI was calculated based on the Clopper–Pearson method.
ep-Value was calculated based on the two-sided Student’s t-test.