Table 7.
Lack of detection of four HIV-2 strains and two HIV-2 primary isolates by the new Alere RDT compared to quantitative PCR
| PCR | New RDT | Virus strain/isolate | HIV-2 group | |
|---|---|---|---|---|
| (c/mL) | Antibody | Ag | ||
| 205,000 | − | − | CBL-20 | A |
| 450,000 | − | − | Rod10 | A |
| 805,000 | − | − | EHO | B |
| 1,000,000* | − | − | ATU | A |
| 1,000,000* | − | − | MVP1845852 | A |
| 1,000,000* | − | − | MVP1847457 | A |
| 0/6 positive (0%) | ||||
Quantitative HIV-2 PCR was performed before measuring RDT reactivity. − non-reactive. *Samples were diluted in PBS to the calculated c/mL before performing the RDT assay