Table 2.
Karyotypes of spontaneous abortions in the primary and secondary RPL groups
| Karyotypes | Primary RPL | Secondary RPL | Total RPL | ||||
|---|---|---|---|---|---|---|---|
| n = 335 | n = 228 | n = 563 | |||||
| n | (%) | n | (%) | n | (%) | ||
| Total normal karyotypes | 188 | 56.1 | 108 | 47.4 | 296 | 52.6 | |
| 46,XX | 113 | 60.1 | 63 | 58.3 | 176 | 59.5 | |
| 46,XY | 75 | 39.9 | 45 | 41.7 | 120 | 40.5 | |
| Total abnormal karyotypes | 147 | 43.9 | 120 | 52.6 | 267 | 47.4 | |
| Single autosomal trisomy | 62 | 42.2 | 47 | 39.2 | 109 | 40.8 | |
| Double trisomy | 1 | 0.7 | 13 | 10.8 | 14 | 5.2 | |
| Sex chromosome trisomies | 4 | 2.7 | 5 | 4.2 | 9 | 3.4 | |
| X monosomy | 13 | 8.8 | 7 | 5.8 | 20 | 7.5 | |
| Autosomal monosomy | 24 | 16.3 | 11 | 9.2 | 35 | 13.1 | |
| Triploidy | 23 | 15.6 | 16 | 13.3 | 39 | 14.6 | |
| Tetraploidy | 2 | 1.4 | 3 | 2.5 | 5 | 1.9 | |
| Structural rearrangements | 2 | 1.4 | 1 | 0.8 | 3 | 1.1 | |
| Combineda | 15 | 10.2 | 10 | 8.3 | 25 | 9.4 | |
| Othersb | 1 | 0.7 | 7 | 5.8 | 8 | 3.0 | |
aCombined – combination of different types of abnormalities (trisomy/polyploidy/monosomy/structural)
bOthers – 46,XX/46,XY chimeras and complete hydatidiform moles with normal karyotypes. Significantly different rates are in bold