Table 6.
Kinetic Analysis of the ex vivo Permeation Data of CEO from Pure CEO, CEO-NE-Based NFs and CEO-NE-Based NEG
| Formula | Coefficients of Determination (R2) | Korsmeyer-Peppas | ||||
|---|---|---|---|---|---|---|
| Zero-Order | First-Order | Higuchi Model | (R2) | Diffusional Exponent (n) | Main Transport Mechanism | |
| Pure CEO | 0.9946 | 0.9939 | 0.9255 | 0.9978 | 1.12 | Super case II transport |
| CEO-NE-based NFs | 0.6569 | 0.6745 | 0.8720 | 0.9235 | 0.45 | Fickian |
| CEO-NE-based NEG | 0.9619 | 0.9401 | 0.8148 | 0.9657 | 1.88 | Super case II transport |
Abbreviations: CEO, clove essential oil; NE, nanoemulsion; NEG, nanoemulgel; NFs, nanofibers.