Table 7.

Drug Retention %, pH, and η at γ of 192 S⁻¹ of CEO-NE-Based NEG Stored at Refrigeration (5 ± 3°C) and Ambient Conditions

Storage time	Evaluation Parameters
	Refrigeration Conditions (5 ± 3°C)			Ambient Conditions
	Drug Retention %	pH	η (cP) at γ of 192 s−1	Drug Retention %	pH	η (cP) at γ of 192 s−1
Zero time	100.00 ± 0.00	4.51 ± 0.01	6545.31 ± 156.89	100.00 ± 0.00	4.51 ± 0.01	6545.31 ± 156.89
1 month	100.40 ± 1.57	4.49 ± 0.01	6545.31 ± 156.89	94.88 ± 0.63	4.46 ± 0.03	4992.19 ± 156.89*
2 months	99.99 ± 2.51	4.49 ± 0.02	6323.44 ± 156.89	91.55 ± 0.95*	4.48 ± 0.02	4548.44 ± 156.88*
3 months	98.22 ± 0.38	4.52 ± 0.01	6212.50 ± 0.00	91.11 ± 3.47*	4.50 ± 0.03	4326.56 ± 156.89*
4 months	98.22 ± 3.14	4.53 ± 0.02	6101.56 ± 156.88	89.66 ± 2.35*	4.85 ± 0.04*	4104.69 ± 156.89*
5 months	96.55 ± 2.98	4.54 ± 0.01	5990.62 ± 0.00	75.85 ± 1.79*	4.75 ± 0.01*	3882.81 ± 156.89*
6 months	96.29 ± 2.48#	4.55 ± 0.03#	5990.62 ± 313.78#	65.48 ± 1.35*	4.77 ± 0.01*	3328.12 ± 313.78*

Notes: Each value represents the mean ± SD (n=3). *Significant at p < 0.05 monthly vs initial. ^#Significant at p < 0.05 refrigeration vs ambient conditions after 6 months.

Abbreviations: CEO, clove essential oil; cP, centipoise; NE, nanoemulsion; NEG, nanoemulgel; η, viscosity; γ, shear rate.