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Frequency of adverse events across cohorts is shown.
| Adverse Event | 72 mg (n = 3) | 108 mg (n = 3) | 144 mg (n = 4) | 216 mg (n = 3) | Overall (n = 13) |
|---|---|---|---|---|---|
| Number of adverse events | |||||
| Abnormal LFTs | 1 | 2 | – | 2 | 5 |
| Fatigue | 1 | – | – | – | 1 |
| Fever | – | 1 | – | – | 1 |
| Rash | – | 1 | 1 | – | 2 |
| Diarrhea | – | – | 1 | – | 1 |
| Edema | – | – | – | 1 | 1 |
| DLT | – | – | – | – | – |
AE- Adverse Event, DLT- Dose Limiting Toxicity, LFT- Liver Function Tests.
