Table 2.
Univariate analysis of metastatic PCa.
Variate | No. | Progression-free survival |
Overall survival |
||||
---|---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | ||
Age (per 1 year) | |||||||
1.002 | 0.976-1.029 | 0.850 | 1.014 | 0.979-1.051 | 0.439 | ||
Gleason score | |||||||
≤6 | 5 | 1 | 1 | ||||
7 | 29 | 9.49 E+08 | 0.980-infinity | 0.052 | 3.97 E+08 | 0.569-infinity | 0.130 |
≥8 | 129 | 1.70 E+09 | 1.840-infinity | 0.008 | 5.80 E+08 | 0.899-infinity | 0.062 |
PSA at diagnosis (per 1 ng/ml) | |||||||
1 | 0.999-1.000 | 0.128 | 1 | 0.999-1.000 | 0.237 | ||
cT stage | |||||||
T1c T2a T2b T2c | 11 | 1 | 1 | ||||
T3a T3b | 107 | 1.802 | 0.664-7.405 | 0.277 | 4.73 E+08 | 1.543-infinity | 0.015 |
T4 | 52 | 3.392 | 1.221-14.082 | 0.015 | 7.56 E+08 | 2.432-infinity | 0.003 |
cN stage | |||||||
N0 | 59 | 1 | 1 | ||||
N1 | 116 | 1.443 | 0.939-2.277 | 0.095 | 1.104 | 0.646-1.941 | 0.720 |
cM stage | |||||||
M0 | 19 | 1 | 1 | ||||
M1 | 157 | 2.365 | 1.125-6.079 | 0.020 | 2.111 | 0.856-7.032 | 0.112 |
Testosterone (per 1 ng/dl) | 1.001 | 0.998-1.003 | 0.388 | 1.001 | 0.998-1.004 | 0.442 | |
Visceral fat percentage (per 1%) | 0.979 | 0.965-0.994 | 0.006 | 0.979 | 0.961-0.997 | 0.029 | |
V/S ratio (per 1) | 1.010 | 0.975-1.029 | 0.446 | 1.009 | 0.921-1.038 | 0.722 | |
Psoas muscle ratio (per 1 cm3/cm) | 1.109 | 0.729-1.651 | 0.901 | 0.593 | 0.316-1.066 | 0.082 | |
BMI (per 1 kg/m2) | 0.943 | 0.881-1.007 | 0.084 | 0.883 | 0.802-0.968 | 0.007 |
Abbreviations: BMI, body mass index;PSA, prostate-specific antigen; V/S ratio, Visceral fat/subcutaneous fat ratio.