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Proportion of responders by eGFR at baseline (COMPOSE-1/COMPOSE-2 intent-to-treat population). *P value for the overall population calculated by Cochran-Mantel-Haenszel test; no statistical analyses were performed for subgroup comparisons.
Abbreviations: eGFR, estimated glomerular filtration rate; NAL, naldemedine, RI, renal impairment.
