Table 5.
Summary of dietary factors associated with nasopharyngeal carcinoma
| Potential risk factor | Summary of results |
|---|---|
|
Alcohol |
Risk factor [78] [S1,S2] |
| Potentially associated [79] [S3] |
|
| No overall association [56,58-73] |
|
| Results inconclusive [S4] |
|
| Result undocumented [S5] |
|
|
Dairy: | |
| Rancid dairy products |
Rancid butter risk factor [61,75] |
| Rancid butter potential association[91] |
|
| Other dairy products |
Milk protective [S5,S6] |
| Milk no association [61,86] |
|
| Butter no association [61] |
|
| Eggs protective [61] [S6] |
|
| Eggs no association [86] |
|
| Salted (duck) eggs (particular time points) risk factor [79,83] |
|
| No association [91] |
|
|
Fish and shellfish: | |
| Salted fish |
Risk factor [57,59,64,65,71,77-82] |
| Inconclusive [83-85] |
|
| No association [59,71,76,85-88] |
|
| Other preserved fish |
Protective [75] |
| Dried fish results inconclusive [83] |
|
| No association [87] |
|
| Fermented fish (sauce) – no association [60,72,84] |
|
| Other fish/shellfish |
Shrimp protective [79] |
| No association [87] |
|
| Fresh fish protective [S6] |
|
| Fresh fish potentially protective [86] |
|
| Fresh fish and other seafood – no association [86] |
|
| Deep sea fish protective [S5] |
|
|
Meat: | |
| Smoked, cured, dried, salted preserved meat |
Risk factor [58] [S1] |
| Risk factor, but not consistent [75,82] |
|
| No association [74,76,86-88] |
|
| Quaddid risk factor [S7] |
|
| Fermented pork no association [72] |
|
| Salted meat no association [72] |
|
| Other meat |
Fresh meat (pork/beef liver) risk factor [79] |
| Red meat risk factor [68] |
|
| Chicken risk factor [S7] |
|
| Chicken protective [91] |
|
| Fried meat – inconclusive association [61] |
|
| Sheep’s tail fat no association [S7] |
|
| Merguez, khelli no association [75] |
|
| Fresh meat no association [86] |
|
| Processed meat no association [S6] |
|
| Sausage no association [72] |
|
|
Other salted products |
Salt-cured food risk factor [68] |
| Salted vegetables risk factor (at least in adulthood) [79,82] |
|
| Salted and dried tomatoes or salted or brined peppers risk factor [61] |
|
| Other salty foods – inconclusive association [61] |
|
| Salted vegetables no association [71] |
|
| Salted mustard greens – inconclusive association [83] |
|
| Salted roots no association [79] |
|
|
Other fermented and preserved foods |
Fermented pastes risk factor[89] |
| Fermented black bean paste and fermented soy bean paste no association[83] |
|
| Fermented foods no association [S1] |
|
| Fermented soy bean products associated [92] |
|
| Fermented soybean products no association [88] |
|
| Fermented and salted vegetables no association [72] |
|
| Preserved vegetables (potential) risk factor [57,65,72] |
|
| Preserved plums risk factor[84,93] |
|
| Preserved vegetables generally risk factor (although salted vegetables and picked Chinese cabbage protective) [93] |
|
| Preserved vegetables no association [86,88] |
|
| Preserved fruit no association [79] |
|
| Pickled vegetables (and fungus on pickles) risk factor [S7] |
|
| Mouldy bean curd no association[84] |
|
|
Vegetables, beans and fruit |
Chung choi not consistently associated, could be risk factor [77] |
| Fresh fruits in childhood protective [81] |
|
| Fresh fruit associated protective [61] |
|
| Fresh fruit and vegetables protective [79] |
|
| Fresh green vegetables protective, others no association [84] |
|
| Fruit and vegetables protective [68] [S6] |
|
| Leafy vegetables protective [85] |
|
| Dark vegetables and fresh fruit protective [S5] |
|
| Grapes protective[91,93] |
|
| Non-preserved fruits and vegetables generally protective [93] |
|
| Cooked vegetables and citrus fruits not consistently associated[75] |
|
| Fresh fruit and vegetables (including green and leafy) no association [74,86] |
|
| Servings per week of fruit and vegetables no association [88] |
|
| Carrots no association[64,66,91] |
|
|
Other: |
|
| Coffee |
No association [73,86] [S6] |
| Tea |
Herbal tea risk factor [85] |
| Green tea protective [86] |
|
| Herbal tea protective [82] |
|
| Protective [65,73] [S4,S6] |
|
| Inconclusive association [61] |
|
| Black, Oolong tea no association [86] |
|
| Slow cooked soup |
Protective [65,82] |
| Dietary nutrients |
Folate, vitamin B6, protective; vitamin B12, methionine no association [S8] |
| Vitamin A, Vitamin C, tocopherol no association [86] |
|
| Beta carotene and vitamin C no association [74] |
|
| Foods containing nitrosamines |
Inconclusive association across all foods [88] |
| Preserves and condiments |
In childhood risk factor [S7] |
| Regular spicy sauce consumption generally risk factor [61] |
|
| No association [75,91] |
|
| Other |
Irregular meals risk factor [61] |
| Adult diet on weaning risk factor [S7] |
|
| Rancid sheep fat risk factor [75] |
|
| Melon seeds risk factor [85] |
|
| Sugary, dried or salted snacks, risk factor [61] |
|
| Food additives risk factor [S9] |
|
| White bread risk factor [S9] |
|
| Lentils protective [91] |
|
| Corn bread protective [S9] |
|
| Margarine and olive oil protective [S9] |
|
| M’hammas no association [S7] |
|
| Potatoes no association [91] |
|
| Grains no association [61] |
|
| Monosodium glutamate no association [85] |
|
| Non-dairy oils and fats no association, unless salted [61] |
|
| Olives no association [75,87] |
|
| Protein, fat, carbohydrate, sodium intake, soybean milk no association [86] |
|
| Olives inconclusive [61] |
|
| French fries – inconclusive association [61] |
|
| General diet – results unclear [95] | |
*References marked with letter S are available in the Online Supplementary Document.