Table 1.

Inclusion and exclusion criteria for SARS-CoV and MERS-CoV systematic review

Inclusion criteria	Exclusion criteria
Studies must be:	1) the main objective was not the study of SARS-CoV or MERS-CoV
- Focused SARS-CoV or MERS-CoV	2) the study was not conducted primarily in a clinical setting (ie, population epidemiology studies, in-vitro studies, surveillance studies were excluded)
- Conducted in a clinical setting	3) the study was not conducted in an outbreak setting or did not analyse data that was collected in an outbreak setting
- Conducted on humans	4) non-human studies
Study designs considered: Observational studies (prospective cohort, retrospective cohort, case-control, case-series) and cross-sectional studies.	5) the sample size was less than 4
	6) the study was not original