Table 3.
Summary of human genetic factors associated with EBV serostatus in the literature
| Risk factor for EBV serostatus | Summary of results |
|---|---|
| Immunological markers | HLA-C variant with the presence of TT at position -35 was more common in EBV seropositive individuals: 1 study [73] |
| Frequency of HLA-Bw4 epitopes was lower in EBV seronegative individuals: 1 study [73] | |
| MBL-insufficient genotype (vs MBL-sufficient genotype) was associated with higher rates of EBV seronegativity: 1 study [23] | |
| No association between haplotype of the β-defensin-1 gene (DEFB1) and EBV seroprevalence: 1 study [91] |
EBV – Epstein-Barr virus, C – cytosine, HLA – human leukocyte antigen, IL – interleukin. MBL – mannose-binding lectin, T – thymine