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. 2020 Mar 23;2020:4061516. doi: 10.1155/2020/4061516

Figure 2.

Figure 2

Behavioral tests and infarct size measurements in MCAo rats after ep-iPSC-NPC transplantation. (a) Behavioral tests of the ep-iPSC-NPC (n = 9), fibroblast (n = 10), and vehicle groups (n = 10) over 12 weeks. Statistical analyses were conducted by two-way ANOVA. ∗p < 0.05 between the ep-iPSC-NPC and fibroblast groups, #p < 0.05 between the ep-iPSC-NPC and vehicle groups. Arrow indicates transplantation. (b) Measurement of infarct size in the ep-iPSC-NPC (n = 5), fibroblast (n = 5), and vehicle groups (n = 5). The infarct area (black dashed line) was measured on eight serial Cresyl violet-stained coronal sections. Data are shown as mean ± standard error of the mean (SEM), ∗p < 0.05 by one way ANOVA. ep-iPSC-NPCs: neural precursor cells differentiated from induced pluripotent stem cells; MCAo: middle cerebral artery occlusion.