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Amino acid sequence alignment of the papain-like proteinase domains of 22 IBV strains indicating the catalytic Cys1274 and His1437 residues marked as asterisks (*) and the more variable region marked by thick bar (—) below the alignment. Residue numbers are given above the sequence; four-digit numbers are ended at the labeled residue. The internal sequences not presented in this alignment are indicated by dashes (–––).
