Table III.
Predictors of current wheeze at 5 years of age in relation to time of atopic sensitization
| Type of ARI | Never atopic OR (95% CI) P value | Atopic by age of 2 years OR (95% CI) P value | Atopic after 2 years OR (95% CI) P value |
|---|---|---|---|
| Whole population regardless of ARI history | 0.4 (0.2-0.8) 0.006∗ | 3.1 (1.5-6.4) 0.05 | 2.9 (1.4-5.8) 0.05 |
| Any wheezy LRI in first year | 1.4 (0.4-5.1) 0.6 | 3.4 (1.2-9.7) 0.02 | 0.5 (0.1-3.5) 0.5 |
| No. of wheezy LRI (linear model) | 1.1 (0.5-2.8) 0.8 | 2.4 (1.2-4.7) 0.01 | 0.9 (0.2-4.1)0.9 |
| 0 | Comparison group | Comparison group | Comparison group |
| 1 | 1.6 (0.4-6.9) 0.5 | 1.9 (0.7-5.5) 0.2 | (≥1) 0.5 (0.1-3.4) 0.5 |
| ≥2 | 1.0 (0.1-9.1) 1.0 | 7.1 (1.3-38.4) 0.02 | NA |
| Any febrile infections in first year | 1.2 (0.4-3.8) 0.8 | 1.2 (0.8-1.8) 0.4 | 1.8 (0.3-9.6) 0.5 |
| Any febrile URI | 1.3 (0.4-4.1) 0.7 | 0.9 (0.5-1.5) 0.9 | 1.4 (0.3-7.1) 0.7 |
| Any febrile LRI | 1.0 (0.2-3.8) 1.0 | 4.2 (1.5-11.8) 0.006 | 1.3 (0.2-9.9) 0.8 |
| Any wheezy or febrile LRI | 1.0 (0.3-3.4) 1.0 | 3.9 (1.4-10.5) 0.007 | 0.7 (0.1-3.9) 0.7 |
| Any wLRI associated with rhinovirus or RSV | 0.8 (0.2-4.0) 0.8 | 4.1 (1.3-12.6) 0.02 | 0.9 (0.1-6.4) 0.9 |
| Any wLRI associated with rhinovirus | 1.6 (0.3-8.7) 0.6 | 3.2 (1.1-9.5) 0.03 | 2.1 (0.3-18.5) 0.5 |
| Any wLRI associated with RSV | 1.6 (0.3-8.7) 0.6 | 3.6 (1.0-13.3) 0.06 | Insufficient number |
NA, Not applicable.
∗
Data in boldface are statistically significant at the .05 level.