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. 2016 Sep 26;126:154–159. doi: 10.1016/j.ejmech.2016.09.080

Table 4.

Dosing schedules for sub-acute toxicology study of RM5061 8a in beagle dogs. The doses shown were administered for 28 consecutive days; for full details, see supporting information.

Indication Grouping Dose employed mg/kg
Systemic exposure to drug 4 groups, ≤10 dogs each (5M/5F) 0 10 30 75