Table 1.
Clinical Characteristics of 10 Patients With AIP*
| Patient/Sex/Age, yr | Smoking Status | Fever | RR, breaths/min | APACHE II Score | Pao2/Fio2 at SLBs | Sx-Adm, d | Adm-MV, d | Adm-SLBx, d | Adm-Steroid, d | PEEP, cm H2O | Vt/kg, mL | Outcome (F/U Duration) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1/F/68 | NS | + | 42 | 12 | 126.9 | 25 | 0 | 2 | 0 | 12 | 7.6 | Died at 32 d |
| 2/F/68 | NS | − | 32 | 9 | 93.3 | 21 | 5 | 7 | 7 | 10 | 8.9 | Survived (75 mo)† |
| 3/M/60 | CS | + | 32 | 13 | 287.3 | 2 | 1 | 3 | 1 | 8 | 7.7 | Survived (78 mo) |
| 4/M/70 | ES | + | 36 | 10 | 196.2 | 4 | 0 | 4 | 3 | 8 | 7.4 | Survived (62 mo) |
| 5/M/57 | CS | + | 36 | 18 | 147.0 | 4 | 1 | 6 | 8 | 16 | 6.4 | Survived (60 mo) |
| 6/M/38 | CS | + | 44 | 10 | 100.5 | 9 | 4 | 5 | 4 | 12 | 7.9 | Survived (59 mo) |
| 7/M/63 | CS | + | 40 | 11 | 231.2 | 5 | 1 | 2 | 4 | 10 | 6.0 | Survived (48 mo) |
| 8/F/70 | CS | + | 38 | 12 | 82.6 | 21 | 1 | 3 | 3 | 14 | 6.1 | Died at 18 d |
| 9/F/73 | NS | + | 40 | 11 | 134.2 | 10 | 0 | 3 | 3 | 10 | 6.1 | Survived (28 mo) |
| 10/M/51 | CS | + | 34 | 15 | 116.0 | 34 | 3 | 9 | 10 | 12 | 6.6 | Survived (12 mo) |
*
M = male; F = female; NS = never smoker; ES = ex-smoker; CS = current smoker; RR = respiration rate; Sx-Adm = time interval from the onset of symptom to hospital admission; Adm-MV = time interval from admission to initiation of mechanical ventilation; Adm-SLBx = time interval from admission to surgical lung biopsy; Adm-Steroid = time interval from admission to the initiation of high-dose steroid therapy; MV = mechanical ventilation; F/U = follow up; Vt = tidal volume; + = yes; − = no.
†
Died due to progression of lung fibrosis 75 months later.