Table 3.
Compound no. | GI50 (μM)a |
|
---|---|---|
MDA-MB-468 | MCF-7 | |
2 | 13.72 ± 0.51 | 11.52 ± 0.25 |
3 | 10.85 ± 0.34 | 8.22 ± 0.10 |
4 | 11.01 ± 0.29 | 51.57 ± 0.59 |
5 | 8.73 ± 0.11 | 36.77 ± 0.45 |
6 | 11.47 ± 0.12 | 13.25 ± 0.28 |
7 | 12.85 ± 0.15 | 14.47 ± 0.31 |
8 | 14.09 ± 0.17 | 12.90 ± 0.27 |
9 | 10.86 ± 0.11 | 14.47 ± 0.33 |
10 | 7.35 ± 0.10 | 14.80 ± 0.35 |
11 | –b | –b |
Chloroquine | 24.36 ± 0.25 | 20.72 ± 0.23 |
Amodiaquine | 17.80 ± 0.09 | 13.01 ± 0.27 |
Mefloquine | 18.25 ± 0.10 | 10.60 ± 0.68 |
GI50, concentration of drug to reduce cell number to 50% of control cultures.
Not determined.