Table 6.
Relationship between management practices suggested for control of transmission of Mycobacterium avium ssp. paratuberculosis and the incidence of calf diarrhea and its associated costs (Canadian dollars; Can$).
| Parameter | Estimate | Reference | Model input1 | ||
|---|---|---|---|---|---|
| Hazard ratio for scour treatment for calves fed non-heat-treated versus heat-treated pooled colostrum | 1.32 (1.14–1.53) | Godden et al., 2012 | Normal (1.32; 0.39) | ||
| Effectiveness of immediate cow-calf separation | Not significant | Quigley et al., 1994, 1995 | — | ||
| Effectiveness of individual calving pens | Not significant | Pithua et al., 2009 | — | ||
| Cumulative incidence of preweaning diarrhea (%) | 20.48 | Waltner-Toews et al., 1986b | Beta (269; 965) | ||
| 24.7 | Wells et al., 1997 | ||||
| Age at first occurrence (d) | 16 | Waltner-Toews et al., 1986b | Normal (16; 2) | ||
| Duration (d) | 3 | Waltner-Toews et al., 1986b | Normal (3; 1) | ||
| Case fatality rate (%) | 5.5–7.1 | Waltner-Toews et al., 1986a | Beta (14.46; 215.13) | ||
| Percentage of total heifer rearing costs before weaning | 12.3 | Gabler et al., 2000 | Beta (4.77; 33.81) | ||
| Daily treatment costs for diarrhea (Can$); light/severe case | 40/2002 | Expert opinion3 | Normal (45.33; 5.66) |
1
Normal=normal distribution (mean; SD); Beta = beta distribution (α; β). 2Assuming 10% of the patients would require intensive treatment for 1 d.3Personal communication with an Alberta dairy practitioner and an ex-practitioner currently employed by a major pharmaceutical company.