Table 2.
Effects of one overdose of the vaccine (6918VP60-T2)
| Group | Vaccination route | Mean body temperature increase (°C) |
Mean body weight increase (g) (0–21 dpva) |
Mean antibody titres |
||
|---|---|---|---|---|---|---|
| 0–2 dpva | 0–4 dpva | Anti-MV | Anti-RHDV | |||
| Vaccinated with 1 dose (104 pfu) | s.c. | 0.2±0.3 | 0.1±0.3 | 206±93 | 8800 | 1035 |
| Vaccinated with 1 dose (104 pfu) | i.d. | 0.3±0.2 | 0.0±0.3 | 200±69 | 9500 | 675 |
| Vaccinated with 10 doses (105 pfu) | s.c. | 0.3±0.3 | 0.1±0.3 | 217±84 | 17800 | 2500 |
| Vaccinated with 10 doses (105 pfu) | i.d. | 0.2±0.4 | 0.2±0.4 | 198±71 | 20000 | 3000 |
| Vaccinated with 100 doses (106 pfu) | s.c. | 0.3±0.5 | 0.3±0.3 | 181±89 | 30000 | 5250 |
| Vaccinated with 100 doses (106 pfu) | i.d. | 0.4±0.6 | 0.2±0.4 | 168±91 | 25000 | 4500 |
| Control (not vaccinated) | 0.2±0.2 | −0.1±0.3 | 220±77 | N.D.b | N.D.b | |
a
dpv: Days postvaccination.
b
N.D.: not detected.