Table 2.
List of the products in phase II, I or pre-clinical trials.
| Product name | Company/institute name | Plant system | Reference/URL |
|---|---|---|---|
| Human serum albumin (HSA) | Chlologen Inc. | Tobacco | Currently technology is with Dow AgroSciences |
| 38C13 (scFv) | Large Scale Biology Corp. | Tobacco | http://www.lsbc.coma |
| RhinoX™ | Planet Biotechnology Inc. | Tobacco | http://www.planetbiotechnology.com/ |
| Alpha inteferon 2b | Biolex Therapeutics Inc. | Lemna | http://www.biolex.com/ |
| DoxoRX™ | Planet Biotechnology Inc. | Tobacco | http://www.planetbiotechnology.com/ |
| α-Caries MAb (CaroX™) | Planet Biotechnology Inc. | Tobacco | http://www.planetbiotechnology.com/ |
| Aprotonin | Large Scale Biology Corp. | Tobacco | http://www.lsbc.coma |
| Collagen | Medicago Inc. | Alfalfa | http://www2.medicago.com/en/product/ |
| Meristem Therapeutics | Tobacco | http://www.meristem-therapeutics.comb | |
| Lipase | Meristem Therapeutics | Maize | http://www.meristem-therapeutics.comb |
| Lactoferrin | Meristem Therapeutics | Tobacco | http://www.meristem-therapeutics.comb |
| Ventria Bioscience | Rice, maize | http://www.ventriabio.com/ | |
| Lysozyme | Ventria Bioscience | Rice | http://www.ventria.com/; |
| BLX-301 (anti-CD antibody) | Biolex Therapeutics Inc. | Lemna | http://www.biolex.com/blx301.htm |
| GLA rich safflower oil | Sembiosys Genetics Inc. | Safflower | http://www.sembiosys.com/ |
| DHA rich safflower oil | Sembiosys Genetics Inc. | Safflower | http://www.sembiosys.com/ |
| Human intrinsic factor | Cobento Biotech AS | Arabidopsis | http://www.cobento.com/ |
| Human glucocerebrosidase | Protalix Biotherapeutics | Carrot suspension cells | http://www.protalix.com/glucocerebrosidase.html |
| Parvovirus vaccine | Large Scale Biology Corp. | Nicotiana | http://www.lsbc.coma |
| Anti-F4 fimbriae of ETEC antibody | Novaplant | Pea (field trials completed 2007) | http://www.novoplant.de/fileadmin/redaktion/seitenspezifische_inhalte/news/pr_FieldTrial_210907.pdf |
| Protein A reagent (Stratocapture™) | Sembiosys Genetics Inc. | Safflower | http://www.sembiosys.com/ |
a
LSBC filed bankruptcy in 2006.
b
Meristem Therapeutics & SBH Sciences has announced an agreement for joint development of animal-free recombinant proteins.