Table 5.
Characteristics of Pandemic H1N1 Patients With and Without Kidney Injury, Kidney Failure, and Requirement for Dialysis
| Kidney Injury |
P | Kidney Failure |
P | Dialysis |
P | ||||
|---|---|---|---|---|---|---|---|---|---|
| No (n = 18) | Yes (n = 30) | No (n = 25) | Yes (n = 25) | No (n = 39) | Yes (n = 11) | ||||
| Age (y) | 28.7 ± 12.3 | 38.4 ± 16.5 | 0.02 | 34.1 ± 15.8 | 36.9 ± 16.1 | 0.5 | 35.4 ± 16.9 | 36.0 ± 11.8 | 0.9 |
| Female | 5/18 (28) | 9/30 (30) | 0.6 | 19/25 (76) | 8/25 (32) | 0.8 | 29/39 (74) | 7/11 (64) | 0.5 |
| Aboriginal | 6/18 (33) | 17/30 (57) | 0.1 | 10/25 (40) | 14/25 (56) | 0.4 | 20/39 (51) | 4/11 (36) | 0.5 |
| Body mass index (kg/m2) | 29.0 ± 2.4 | 38.5 ± 2.4 | 0.02 | 31.3 ± 2.3 | 39.1 ± 2.8 | 0.04 | 34.1 ± 2.2 | 37.2 ± 3.5 | 0.5 |
| Diabetes mellitus | 3/18 (17) | 13/30 (43) | 0.07 | 8/25 (32) | 9/25 (36) | 0.5 | 13/39 (33) | 4/11 (36) | 0.9 |
| Hypertension | 2/18 (11) | 9/30 (30) | 0.3 | 4/25 (16) | 7/25 (28) | 0.2 | 7/39 (18) | 4/11 (36) | 0.2 |
| Pregnancy | 4/18 (22) | 4/30 (13) | 0.5 | 5/25 (20) | 3/25 (12) | 0.4 | 6/39 (15) | 2/11 (18) | 0.9 |
| Asthma | 1/18 (6) | 11/30 (37) | 0.02 | 1/24 (4) | 11/25 (44) | <0.001 | 9/39 (23) | 3/11 (27) | 0.9 |
| Glasgow Coma Scale | 10.3 ± 1.3 | 10.6 ± 1.0 | 0.9 | 9.7 ± 1.2 | 10.7 ± 1.0 | 0.5 | 10.8 ± 0.8 | 7.9 ± 1.8 | 0.2 |
| APACHE II score | 16.3 ± 1.8 | 20.9 ± 1.1 | 0.04 | 17.5 ± 6.6 | 21.1 ± 6.0 | 0.06 | 18.9 ± 6.6 | 20.3 ± 6.4 | 0.5 |
| BP support agents | 9/18 (50) | 23/30 (77) | 0.1 | 13/25 (52) | 20/25 (80) | 0.07 | 24/39 (62) | 9/11 (82) | 0.3 |
| MAP (mm Hg) | 67.7 ± 15.1 | 78.5 ± 17.9 | 0.05 | 69.5 ± 15.5 | 78.7 ± 18.4 | 0.07 | 72.0 ± 15.9 | 80.1 ± 21.2 | 0.1 |
| WBC (×109/L) | 8.6 ± 2.0 | 9.0 ± 1.4 | 0.9 | 9.4 ± 1.5 | 11.7 ± 3.8 | 0.6 | 12.1 ± 2.5 | 5.3 ± 1.8 | 0.04 |
| Creatine kinase (μmol/L) | 667.5 ± 203.8 | 646.1 ± 186.3 | 0.9 | 680.9 ± 166.9 | 592.4 ± 219.3 | 0.8 | 567.3 ± 122.8 | 860.0 ± 428.4 | 0.4 |
| ICU length of stay (d) | 17.8 ± 3.7 | 25.5 ± 3.5 | 0.2 | 20.2 ± 3.2 | 24.7 ± 4.0 | 0.4 | 19.3 ± 2.6 | 33.3 ± 6.4 | 0.02 |
| Dialysis | 0/15 (0) | 11/18 (61) | 0.008 | 0/25 (0) | 11/25 (44) | <0.001 | NA | NA | NA |
| Death | 1/18 (6) | 7/30 (23) | 0.2 | 1/25 (4) | 8/25 (32) | 0.02 | 7/39 (18) | 2/11 (18) | 0.9 |
Note: Values expressed as mean ± standard deviation or number of patients (percentage). No conversion necessary for WBC count in 109/L and 103/μL.
Abbreviations: APACHE, Acute Physiology and Chronic Health Evaluation; BP, blood pressure; MAP, mean arterial pressure; NA, not applicable; WBC, white blood cell count.