Fig. 2.

Phylogenetic relationships of mesoniviruses.

Phylogenetic trees of mesoniviruses and representative nidoviruses based on amino acid sequences of RdRp and spike proteins were conducted by the Maximum-likelihood (ML) method, a NJJ substitution matrix, and no distance correction in MEGA 6.06. Significance was tested by bootstrap analysis using 1000 resampling steps. The scale bars represent number of substitutions per amino acid position on average.

(a) Rooted based on RdRp protein and including roniviruses as outgroup.

(b) two unrooted of mesoniviruses and based on spike and RdRp proteins