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. 2013 Apr 13;21(12):3555–3564. doi: 10.1016/j.bmc.2013.04.002

Scheme 7.

Scheme 7

Synthesis of cNGR/Gd(III)-DTPA loaded quantum dots. The cNGR moieties allow for the multivalent targeting of CD13 expressing cells, while coupling with multiple dendritic constructs, each containing 8 Gd(III) ions per molecule allows for locally high concentrations of Gd(III), which is optimal for MRI.