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(A) Comparison of the neuraminidase of various N2 subtypes. A typical 20 aa deletion is observed in the stalk region for chicken isolates, although the A/chicken/Texas/298313/04 (H5N2) isolate has a distinct 13 aa deletion slightly upstream from the rest. (B) Phylogenetic trees of the full-length NA genes based on nt sequence alignment. The four LPAI H5 isolates F118, F189, F59 and F119 are boxed while high pathogenic influenza isolates are highlighted in grey.
