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. 2019 Feb 2;27(6):1023–1033. doi: 10.1016/j.bmc.2019.02.005

Table 2.

Inhibitory activity of tricyclic PCV derivatives (9) against HSV and cytotoxicity data. The grey shades highlight the most interesting data.

graphic file with name fx20_lrg.gif

aRequired to reduce virus-induced cytopathogenicity by 50%.

bRequired to cause a microscopically detectable alteration of normal cell morphology.

Aciclovir (ACV), Brivudin (BVDU), Cidofovir (CDV), Ganciclovir (GCV).