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Time from the end of study drug infusion to a 24-hour apnea-free period. Accelerated failure time analysis shows a geometric mean time for the caffeine group 28.7 hours (95% CI, 25.6-32.3 hours) and 29.1 hours (95% CI, 25.7-32.9 hours) for the placebo group (OR, 0.99; 95% CI, 0.83-1.17; P = .88).
