Table 2.

Summary of total symptom scores (Days 1–8).

	PrEP-001	Placebo
Study 1
N	22	22
Median (range)	4.5 (0–71)	38.5 (0–106)
Mean (SE)	10.2 (3.89)	40.6 (7.18)
95% CI	2.1, 18.3	25.7, 55.5
Difference PrEP-001/placebo	−30.4
95% CI	−46.9, −13.9
Study 2
N	25	27
Median (range)	4 (0–39)	8 (0–92)
Mean (SE)	9.1 (1.83)	20.6 (3.97)
95% CI	5.3, 12.9	12.3, 28.9
Difference PrEP-001/placebo	−11.5
95% CI	−20.1, −2.9