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. 2004 Oct 4;239:47–97. doi: 10.1016/S0074-7696(04)39002-9

FIG. 1.

FIG. 1

Components of the renin–angiotensin system with the principal enzymes ACE and ACE2 involved in the generation of biologically active peptides. ▴; vasoconstrincting effect; ●; vasodilating effect.