Table 2.
Genotype and allele analyses of the IFITM1 gene polymorphisms in the UC patients and the healthy controls.
| Positiona | Genotype/allele | Control n (%) |
UC n (%) |
Odds ratiob (95% CI) | Pc |
|---|---|---|---|---|---|
| g.-1920G>A (rs77537847) | AA | 198 (38.8) | 46 (36.8) | 1.00 | 0.002 |
| AG | 248 (48.6) | 48 (38.4) | 0.83 (0.53–1.30) | ||
| GG | 64 (12.5) | 31 (24.8) | 2.09 (1.22–3.56) | ||
| A | 644 (63.1) | 140 (56.0) | 1.00 | 0.04 | |
| G | 376 (36.9) | 110 (44.0) | 1.35 (1.02–1.78) | ||
| g.-416C>G (rs11246062) | CC | 322 (64.1) | 69 (59.5) | 1.00 | 0.35 |
| CG | 180 (35.9) | 47 (40.5) | 1.22 (0.81–1.84) | ||
| GG | 0 (0.0) | 0 (0.0) | – | ||
| C | 824 (82.1) | 185 (79.7) | 1.00 | 0.40 | |
| G | 180 (17.9) | 47 (20.3) | 1.16 (0.81–1.66) | ||
a
Calculated from the translation start site.
b
Logistic regression analyses were used for calculating OR (95% CI; confidence interval).
c
Value was determined by Fisher's exact test or χ2 test from a 2 × 2 contingency table.