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. 2006 Jul 18;14(7):1157–1165. doi: 10.1016/j.str.2006.05.012

Table 2.

A Comparison of the Hydrophobic Pockets of Different Types of Lipid Binding Proteins

Protein Structure PDB Code (Literature Reference) Type of Ligand Volume of the Pore (Å3) Volume of the Ligand in the Pore (Å3) Percentage of Pore Occupied
SARS-CoV ORF-9b 2CME Long-chain fatty acid 365 166 45%
Human CD1b 1GZP (Gadola et al., 2002) Ganglioside GM2 (glycolipid) 1564 881 56%
Poliovirus 2PLV (Filman et al., 1989) Sphingosine (long-chain amino alcohol) 292 176 60%