Table 2.
A Comparison of the Hydrophobic Pockets of Different Types of Lipid Binding Proteins
| Protein Structure | PDB Code (Literature Reference) | Type of Ligand | Volume of the Pore (Å3) | Volume of the Ligand in the Pore (Å3) | Percentage of Pore Occupied |
|---|---|---|---|---|---|
| SARS-CoV ORF-9b | 2CME | Long-chain fatty acid | 365 | 166 | 45% |
| Human CD1b | 1GZP (Gadola et al., 2002) | Ganglioside GM2 (glycolipid) | 1564 | 881 | 56% |
| Poliovirus | 2PLV (Filman et al., 1989) | Sphingosine (long-chain amino alcohol) | 292 | 176 | 60% |