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. 2010 Sep 19;18(22):7940–7947. doi: 10.1016/j.bmc.2010.09.035

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Copyright © 2010 Elsevier Ltd. All rights reserved.

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(A) Dixon plot for inhibition of amentoflavone (9) on 3CL^pro for the proteolysis of substrate. In the presence of difference concentrations of substrate: 2.5 μM (▾), 5.0 μM (○), and 10.0 μM (●). (B) The plot of V_max versus inhibitor concentrations for determining the inhibition type.