Table 2.
Characteristics and Laboratory Findings in a Cluster of SARS Patients
| HCWs (n = 4) | Non-HCWs (n = 12) | p Value | |
|---|---|---|---|
| General data⁎ | |||
| Age (years) | 28.0 ± 1.4 | 47.8 ± 18.2 | 0.051 |
| Female/male | 3/1 | 7/5 | NS |
| Lymphopenia | |||
| Peak (× 106/L) | 299.8 ± 197.1 | 355.0 ± 249.8 | NS |
| On fever day† | 10.5 ± 3.3 | 10.3 ± 3.8 | NS |
| Thrombocytopenia | |||
| Peak (× 109/L) | 157.8 ± 96.5 | 147.8 ± 54.8 | NS |
| On fever day | 7.3 ± 1.9 | 7.8 ± 3.5 | NS |
| Lactate dehydrogenase elevation | |||
| Peak (U/L) | 426.0 ± 335.2 | 434.9 ± 190.0 | NS |
| On fever day | 10.3 ± 2.4 | 12.3 ± 3.7 | NS |
| Creatine kinase elevation | |||
| Peak (U/L) | 140.3 ± 64.1 | 210.7 ± 130.2 | NS |
| On fever day | 8.5 ± 1.3 | 9.2 ± 4.7 | NS |
| Aspartate aminotransferase elevation | |||
| Peak (U/L) | 92.8 ± 79.9 | 79.5 ± 44.3 | NS |
| On fever day | 13.3 ± 3.0 | 10.8 ± 4.4 | NS |
| Alanine aminotransferase elevation | |||
| Peak (U/L) | 129.0 ± 94.9 | 107.8 ± 49.3 | NS |
| On fever day | 14.8 ± 1.7 | 14.9 ± 4.6 | NS |
| C-reactive protein elevation | |||
| Peak (mg/Dl) | 3.5 ± 4.0 | 11.0 ± 6.1 | 0.038 |
| On fever day | 11.8 ± 1.3 | 11.9 ± 4.0 | NS |
| Desaturation | |||
| Peak (pO2/FiO2 ratio) | 274.5 ± 58.6 | 167.6 ± 91.9 | 0.049 |
| On fever day | 12.5 ± 3.1 | 11.9 ± 2.2 | NS |
| Intubation and mortality | |||
| Intubation | 0/4 | 4/12 | 0.516 |
| Mortality | 0/4 | 3/12 | 0.529 |
⁎
Data are presented as mean ± SD. NS = not significant.
†
On fever day indicates when the laboratory abnormalities peaked in relation to the number of days after the onset of documented fever > 38°C.