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. 2010 Nov 2;133(2):718–723. doi: 10.1016/j.jep.2010.10.059

Fig. 2.

Fig. 2

Effects of emodin on viral titers change on HSV-infected mice. (A) Viral titer in brains from HSV-1 infected mice, (B) viral titer in hearts from HSV-1 infected mice, (C) viral titer in livers from HSV-1 infected mice, (D) viral titer in ganglions from HSV-1 infected mice, (E) viral titer in brains from HSV-2 infected mice, (F) viral titer in hearts from HSV-2 infected mice, (G) viral titer in livers from HSV-2 infected mice, (H) viral titer in ganglions from HSV-2 infected mice; mice were infected with HSV-1 and HSV-2 as described in Section 2. The mice were treated with different doses of emodin of 3.3 (▴), 6.7 (◆), or 11.3 g/kg/day (■) or with 0.9% NaCl as a control (×) for 7 days beginning 24 h after infection. Viral titers represent geometric mean ± SD per organ of the mice in each group. The *6.7 g/kg/day and **11.3 g/kg/day emodin group started to show significantly reduced virus titers of mice organ homogenates at day 6 after infection compared to 0.9% NaCl group (p < 0.05).