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. 2002 May 25;289(5):1283–1299. doi: 10.1006/jmbi.1999.2850

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Copyright © 1998 Academic Press. All rights reserved.

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(a) The mIAP gag-pro frameshift site (Fehrmann et al., 1997). The slip site heptamer is enclosed in a box and the pseudoknot structural elements are annotated. The structure of this pseudoknot has yet to be determined. The adenosine at the junction (A15), shown unpaired in this model, may be paired with the final uridine in loop 2 (U31) and it is not clear which of the two adenosine bases (A35 and A36) in stem 2 is paired with U11. (b) Mutations incorporated in the mIAP pseudoknot sequence. The double mutant, ΔA35A15 RNA, is indicated by the open circles.