Fig 1.

The Risk-Based Decision-Making framework. The Risk-Based Decision-Making framework was designed by the Alliance of Blood Operator to help blood operators identify, assess, act on, and communicate risk in decisions related to blood safety. It is a flexible tool, and its objectives are to optimize the safety of the blood supply while recognizing that elimination of all risk is not possible; allocate resources in proportion to the magnitude and seriousness of the risk and the effectiveness of the interventions to reduce risk; and assess and incorporate the social, economic, and ethical factors that may affect decisions about risk [23], [24], [25].