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. 2017 May 4;38(2):233–248. doi: 10.1016/j.ccm.2016.12.007

Table 2.

Pulmonary toxicity of chemotherapeutic and immunosuppressive agents

Agent Pulmonary Toxicity
Known pulmonary toxicity in HCT
 Carmustine Acute pneumonitis
 Cyclosporine Capillary leak (noncardiogenic pulmonary edema), ARDS
 Sirolimus Organizing pneumonia, DAH, ARDS, pulmonary alveolar proteinosis
Known pulmonary toxicity in other clinical settings
 Cyclophosphamide Interstitial pneumonia, organizing pneumonia
 Fludarabine Interstitial pneumonitis, acute eosinophilic pneumonia
 Azathioprine Organizing pneumonia, DAH, interstitial pneumonitis, laryngeal edema, vasculitis
 Tacrolimus Organizing pneumonia
 Mycophenolate mofetil Pulmonary edema, ARDS, pulmonary fibrosis, bronchiectasis
 Rituximab anti-CD-20 antibody ARDS, DAH, interstitial pneumonitis, organizing pneumonia, pulmonary fibrosis, hypersensitivity pneumonitis
 Alemtuzumab anti-CD52 antibody DAH