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. 2018 Sep 6;36(4):665–683. doi: 10.1016/j.emc.2018.07.001

Table 5.

Treatment of adults with community-acquired pneumonia

Patient Characteristics Regimen
Outpatient: previously healthy Macrolide
Doxycycline
Outpatient: with comorbidities (heart, lung renal disease, diabetes, alcoholism) or recent use of antibiotics concerning for drug-resistant Streptococcus pneumoniae Respiratory fluoroquinolone
Beta-lactam plus macrolide
Outpatient: macrolide-resistance streptococcus areas (>25% of infection) Respiratory fluoroquinolone
Beta-lactam plus macrolide
Inpatient: floor Respiratory fluoroquinolone
Beta-lactam plus macrolide
Inpatient: intensive care unit Beta-lactam plus azithromycin or respiratory fluoroquinolone
Penicillin allergic: respiratory fluoroquinolone plus aztreonam
Inpatient: Pseudomonas Antipseudomonal beta-lactam such as piperacillin-tazobactam, cefepime, meropenem, imipenem plus ciprofloxacin or levofloxacin
Inpatient: methicillin-resistant Staphylococcus aureus Vancomycin or linezolid