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. 2019 Dec 12;140:103922. doi: 10.1016/j.micpath.2019.103922

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Fig. 8 — Necropsy examinations, histopathology and immunohistochemical (IHC) of the intestines of piglet inoculated with PEDV HM2017 strain (P15) at 36 hpi. (A) Necropsy examinations of the intestines from HM2017-inoculated group and control group. (a) The control group showing no intestinal lesions. (b–c) The small intestines of HM2017-inoculated group showing distended, transparent, and filled with yellow fluid. (B) Hematoxylin and eosin-stained small intestinal sections from HM2017-inoculated group and control group (200× magnification). (a) The normal small intestinal villus was observed in control group. (b–c) The shortening, fusion, and sloughing of the small intestinal villus was observed in HM2017-inoculated group. (C) Detection of PEDV antigen by IHC analysis of small intestinal sections from HM2017-inoculated group and control group (200× magnification). (a) No PEDV antigen was detected in small intestines from control group. (b–c) PEDV antigen (brown color) was detected in small intestine epithelial cells from HM2017-inoculated group.