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Controversies around the use of corticosteroid therapy in SARS
| Pros | Cons |
|---|---|
| Clinical and radiological responses have been observed Suppression of inflammatory cytokines |
Metabolic complications: hyperglycemia, hypertension, hypokalemia Increased bacterial superinfections Avascular osteonecrosis; but incidence was low (0.6%) if total prednisolone dose was <3 g Reduced viral clearance Others (eg, acute psychosis) |
