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. 2017 Jul 24;115:74–83. doi: 10.1016/j.jct.2017.07.027

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© 2017 Elsevier Ltd.

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Fig. 4 — Mole fraction solubility (x) of ribavirin in 1,4-dioxane (w) + water (1 − w) mixed solutions with various mass fractions at different temperatures: w, mass fraction of 1,4-dioxane; □, w = 0; ○, w = 0.0994; ♢, w = 0.2009; ☆, w = 0.3011; △, w = 0.4007; ■, w = 0.4999; ●, w = 0.5988; ▲, w = 0.7003; ◆, w = 0.7998; ★, w = 0.8992; ▾; w = 1. —, calculated curves by the Jouyban − Acree model.