Fig. 3.

FMDV inhibits PKR activation. (A) PK-15 cells were mock-infected or infected with FMDV (0.5 MOI) for 0, 3, 6, 12 or 18 h. The expression levels of PKR, p-PKR, eIF-2α and p-eIF-2α levels were detected by western blotting. (B) PK-15 cells were transfected with 1 μg of empty vector or poly(I:C); and the cells were mock-infected or infected with FMDV (0.5 MOI) for 12 h. The expression levels of PKR and p-PKR levels were detected by western blotting.