Table 1.
Cytotoxicity of taxchinin A, brevifoliol and their derivatives against A549 cell linea
Compound | IC50 (μM) | Compounds | IC50 (μM) |
---|---|---|---|
1 | 60.50 | 13 | 3.16 |
2 | NA | 14 | NA |
3 | 91.62 | 15 | 0.75 |
4 | 1.68 | 16 | 46.47 |
5 | NA | 17 | 6.17 |
6 | 6.22 | 18 | 2.80 |
7 | 31.62 | 19 | 2.48 |
8 | 87.33 | 20 | 21.52 |
9 | 12.39 | 21 | 80.72 |
10 | NA | 22 | 17.37 |
11 | 0.48 | 23 | 11.27 |
12 | 5.89 | DDP | 2.10 |
NA, not active; IC50 values greater than 100 μM were considered as inactive and represented as NA.