Tension recordings in BAMG-regenerated and host bladder strips 4 months after surgery
Strip Weight (mg.) | Tetrodotoxina (gm.) | Atropine Sulfateb (gm.) | Valethamate Bromideb (gm.) | Isoproterenolc (gm.) | Norepinephrinec (gm.) | Nitroprussided (gm.) | |
---|---|---|---|---|---|---|---|
BAMG- | 29.5 ± 4.0† | 1.86 ± 0.3 | 1.94 ± 0.58 | 0.76 ± 0.04 | 0.98 ± 0.351 | ||
Regenerates | 1.13 ± 0.48 | 0.0 ± 0.04* | 0.0 ± 0.03* | 0.0 ± 0.01* | 0.0 ± 0.02* | 0.65 ± 0.1 | |
(N = 19) | (N = 3) | (N = 3) | (N = 3) | (N = 2) | (N = 2) | (N = 4) | |
Host | 37.2 ± 2.5 | 2.26 ± 0.43 | 2.42 ± 0.66 | 0.73 ± 0.04 | 2.03 ± 0.35 | ||
Bladder | 0.81 ± 0.5* | 0.0 ± 0.03* | 0.0 ± 0.03* | 0 ± 0.04* | 0 ± 0.03* | 1.69 ± 0.3 | |
(N = 30) | (N = 3) | (N = 5) | (N = 5) | (N = 2) | (N = 2) | (N = 8) |
With supramaximal elecrical field stimulation before (upper line) and after administration of tetrodotoxin 0.4 × 10−6 M (lower line).
15 min. after carbachol stimulation 10−4 M (upper line) and after subsequent administration of atropine sulfate 10−6 M and valethamate bormide 2.6 × 10−5 M (lower line).
Before (upper line) and after (lower line) administration of isoproterenol 10−4 M and norepinephrine 5.6 × 10−4 M.
15 min. after potassium stimulation alone (upper line) and after subsequent administration of nitroprusside 10−4 M (lower line).
p<0.05 when compared with tension before administration of the drug.
p<0.05 when compared with host bladder strips.