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. 2015 May 6;23(13):3135–3146. doi: 10.1016/j.bmc.2015.04.079

Table 1.

Isoxazolidines trans-9 and cis-9 obtained according to Scheme 3

Entry Acrylamide 11 Ratio of trans-9/cis-9 Yield (%)
R
A graphic file with name fx2_lrg.gif 81:19 trans-9a (63)a + cis-9a (11)a + trans-9a and cis-9a (11)b
B graphic file with name fx3_lrg.gif 84:16 trans-9b (71)a + cis-9b (14)a + trans-9b and cis-9b (2)b
C graphic file with name fx4_lrg.gif 79:21 trans-9c (67)a + cis-9c (19)a + trans-9c and cis-9c (5)b
D graphic file with name fx5_lrg.gif 79:21 trans-9d (33)a + cis-9d (8)a + trans-9d and cis-9d (52)b
E graphic file with name fx6_lrg.gif 86:14 trans-9e (32)a + cis-9e (11)a + trans-9e and cis-9e (54)b
F graphic file with name fx7_lrg.gif 78:22 trans-9f (31)a + cis-9f (8)a + trans-9f and cis-9f (50)b
a

Yield of pure isomer.

b

Yield of pure mixture of cis- and trans-isomers.