Table 2.
Oligomeric form of DNA helicases
| Helicase | Oligomeric form |
|---|---|
| E. coli helicase IIa | Dimer |
| E. coli helicase III | Dimer |
| E. coli Rep | Dimer |
| HeLa helicase α | Dimer |
| HDH II/Ku | Dimer (heterodimer) |
| Pea chloroplast helicase I | Dimer |
| HSV-1 origin binding protein | Dimer |
| Herpes helicase/primase | Dimer (heterodimer) |
| E. coli DnaB | Hexamer |
| E. coli Rho | Hexamer |
| E. coli RuvB | Hexamer |
| M. thermoautrophicum MCM | Hexamer |
| T7 gene 4 (E. coli phage) | Hexamer |
| T4 gene 41 (E. coli phage) | Hexamer (requires GTP) |
| SSP1 gene 40 (B. subtilis phage) | Hexamer |
| Plasmid encoded RSF1010 RepA | Hexamer |
| SV40 large T antigen | Hexamer |
| Bovine papillomavirus E1 | Hexamer |
| HhcsA | Hexamer |
| MCM | Hexamer |
| Bloom's syndrome helicase | Hexamer |
| E. coli RecB | Oligomer (dimer-tetramer) |
| E. coli UvrAB complex | Oligomer (hetero oligomer) |
| E. coli RecBCD | Oligomer (heterotrimer) |
Note: Examples of monomeric DNA helicases are mentioned in the text.
a
E. coli Helicase II (UvrD) is also active as a monomer.