Table 3.
Polarity of biochemically active DNA helicases
| 3′–5′ DNA helicases | 5′–3′ DNA helicases |
|---|---|
| Bacterial: helicase II, helicase IV, PriA, Rep, RecQ, RecB, RecG, PcrA (E. coli), PcrA (Bacillus) | Bacterial: helicase I, helicase III, DnaB, UvrAB complex, RuvAB, Rho, RecD, DinG, PcrA (Bacillus) |
| Bacteriophage: P4geneα | Bacteriophage: T4gene 41, T4 dda, T7 gene 4, SSP1-G40P |
| Viral: SV40 T-antigen, Polyoma T-antigen, HSV-1 (UL9), BPV-1 (E1 protein), AAV (Rep68, Rep 78), AAV-Rep40, Vaccinia virus A18R, MBP-Rep52 (AAV) | Viral: HSV-1 (UL5/UL8/UL52), LEF-3, SARS-CoV helicase (Coronoviridae helicase) |
| Plasmodium: P. cynomolgi DNA helicase, P. falciparum DNA helicase | Plasmodium: P. falciparum DNA helicase |
| Yeast: helicase I, Rad 25 (ssl2), Srs2, Sgs1, MCM, MER3 | Yeast: Rad3, PIF1, RFC associated helicase, helicase A, helicase B, ScHelI, helicase III, Dna2 |
| Frog: Xenopus laevis ovarian DNA helicase I | Frog: Not reported so far |
| Fruitfly: Dhel III, DmRecQ5 | Fruitfly: Dhel I, dhel II |
| Calf thymus: helicase A, helicase E (ε), helicase I, helicase II, cytosolic helicase, Bovine mitochondrial helicase (57 kDa) | Calf thymus: helicase B, helicase C, helicase D, helicase F, helicase δ |
| Human: Human DNA helicase (HDH) I, HDH II/Ku, HDH III, HDH V, HDH VI, TFIIH, [ERCC3 (XPB)], helicase α, helicase ε, RIP100, helicase Q1, WRN, BLM, MCM 4/6/7, REQ1, hFBH1, HEL308, RECQ1. | Human: HDH IV, HDH VIII, ERCC2 (XPD), helicase Q2, HchlR1, HhcsA, BACH1 |
| Mouse/Rat: Rat T1P49a | Mouse/Rat: Mouse ATPase C1, Mouse ATPase B |
| Plant: Pea chloroplast DNA helicase I and II, Pea nuclear DNA helicase (PDH) 45, PDH65, PDH120, PDH47, At-Ku70/80 | Plant: Pea nucleolar DNA helicase (PNDH), PDH47 |