Scheme 2.
Synthesis of C-terminal side-chain-modified compounds (B). Reagents: (a) 20% pip/DMF; (b) Fmoc-Xaa-OH/DIC/HOBt/DMF; (c) 2/DIC/HOBt/DMF; (d) TFA/H2O/TIPS (95:4:1).
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.