Table 1.
Viral protein glycan structure, function and host glycoprotein interaction
Virus protein | Glycan structure | Role | Host glycoprotein | Refs |
---|---|---|---|---|
Influenza HA | High mannose | Attachment | MBL | [64] |
GlcNAc | Release | SP-D | 72, 73 | |
Glycan shield? | MMR | [52] | ||
Gp340 | 74, 75 | |||
HIV-1 gp120 | High mannose | Attachment | MBL | 76, 77 |
Hybrid | Glycan shield | SP-D | [67] | |
Sialic acid | DC-SIGN | 46, 78 | ||
DC-SIGNR | [46] | |||
MMR | [53] | |||
Hepatitis C virus E1, E2 | High mannose | Infectivity | DC-SIGN | [79] |
Entry | L-SIGN | [55] | ||
West Nile virus E | High mannose | Replication | DC-SIGN | 57, 80 |
Fucose | Neuroinvasion | DC-SIGNR | ||
SARS-CoV S, M | High mannose | Assembly | LSECtin | 59, 62 |
Hybrid | Attachment | DC-SIGN | ||
GalNAc | ||||
Ebola GP | High mannose | Infectivity | DC-SIGN | [58] |
DC-SIGNR |