Table 2.

Description of model parameters with their baseline values for influenza infection obtained from the published literature (Ferguson et al., 2005, Handel et al., 2006, Longini et al., 2005, Regoes and Bonhoeffer, 2006).

Parameter	Description	Baseline value (range)	Unit
$\beta$	Transmission rate of the sensitive strain	Variable	$(\text{day people}{)}^{-1}$
$p$	Treatment level of infected individuals	Variable (0-1)	–
${\delta }_T$	Relative transmissibility of treated sensitive infection	0.4	–
${\delta }_r$	Relative transmissibility of the resistance strain	0.8 (0-1)	–
${\alpha }_T$	Rate of developing resistance during treatment	${10}^{-4}$$({10}^{-6}-{10}^{-1})$	${\mathrm{day}}^{-1}$
${\gamma }_U$	Recovery rate of untreated infection	1/4.1	${\mathrm{day}}^{-1}$
${\gamma }_T$	Recovery rate of treated infection	1/4.1	${\mathrm{day}}^{-1}$
$d_U$	Disease-induced death rate of untreated sensitive infection	0.002	${\mathrm{day}}^{-1}$
$d_T$	Disease-induced death rate of treated sensitive infection	0.0002	${\mathrm{day}}^{-1}$
$d_{{}_{U,r}}$	Disease-induced death rate of resistant infection	$\sim {\delta }_r{d}_U$	${\mathrm{day}}^{-1}$
$R_0^s$	Basic reproduction number	Variable (1–3)	–

For a particular value of $R_0^s$, the transmission rate of the sensitive strain can be obtained using the expression $\beta =R_0^s(d_U+{\gamma }_U)/S_0$.