Table 3.
Humoral immune responses determined by IFAT, ELISA with crude antigen and ELISA rK39
| Glucantime® |
Glucantime® + Leish-110f®/MPL-SE® |
Leish-110f®/MPL-SE® |
MPL-SE® |
Placebo |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n = 6 | n = 4 | n = 6 | n = 5 | n = 6 | n = 6 | n = 6 | n = 5 | n = 6 | n = 3 day | |
| Day 0 | Day 180 | Day 0 | Day 180 | Day 0 | Day 180 | Day 0 | Day 180 | Day 0 | Day 180 | |
| IFAT (antibody titer) | 3733.3 ± 3538.4 | 1520 ± 1208 | 7466.7 ± 7076.8 | 480.0 ± 226.3 | 17493 ± 31579 | 17520 ± 5120 | 5573 ± 4058 | 6672 ± 7997 | 5720 ± 8186 | 1706 ± 739 |
| ELISA crude antigen (antibody titer) | 1173.3 ± 1083.6 | 300.0 ± 247.6 | 1013.3 ± 820.0 | 256.0 ± 87.6 | 4533 ± 4765 | 2468 ± 1568 | 1400 ± 1894 | 3200 ± 1280 | 2226 ± 3962 | 426.6 ± 184.7 |
| ELISA rK39 (antibody titer) | 3733.0 ± 3870.0 | 1800.0 ± 2260.0 | 16426 ± 19330 | 5180.0 ± 5842.0 | 25013 ± 31881 | 14080 ± 14971 | 4293 ± 3459 | 28688 ± 33478 | 4186 ± 8035 | 14506 ± 22909 |
Values are m ± σ. Values are expressed as mean of antibody titers by groups at day 0 and 180 after therapy. σ: standard deviation, n: numbers of dogs evaluated.